KMID : 0358820060330060757
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Journal of Korean Society of Plastic and Reconstructive Surgeons 2006 Volume.33 No. 6 p.757 ~ p.760
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Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Report
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Yoo Jung-Seok
Lee Dong-Lark Lim Jun-Kyu Yoon In-Mo Lee Byung-Du Lee Dong-Eun
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Abstract
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Purpose:Anaplastic large cell lymphoma, has the following three characteristics of a malignant lymphoma; 1) An irregular large nucleus, called pathologic atypical cells, 2) Eosinophilic cytoplasm, 3) Immunologically positive for Ki-1. Anaplastic large cell lymphoma occurs mostly in the lymph nodes, but about 40% has been observed to occur in other tissues. Skin is the one of the main sources of origin and it is called ¡¯primary cutaneous anaplastic large cell lymphoma¡¯.
Methods:A 69-year-old male patient with an erythematous nodule, sized 1.5 X 1.7 cm on his right hand dorsum was excised under local anesthesia and on biopsy was diagnosed as ¡¯Dermatofibrosarcoma Protuberans¡¯. Three months after the local excision and biopsy, same natured mass reoccurred in the same region, and then spontaneous regressed after three weeks. However, metastatic large mass of 4.0 X 5.0 cm, of same nature was observed on the elbow. The large mass was operated with wide excision and biopsy.
Results: On final diagnosis, with an immunofluorescent stain with CD30(Ki-1), ¡¯Primary cutaneous large cell lymphoma¡¯ was made. After follow up for three years, we did not observed recurrence and metastasis.
Conclusions:We have reported that we have diagnosed primary cutaneous large cell lymphoma and treated without recurrence and metastasis.
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KEYWORD
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Lymphoma, Large-cell, Ki-1, CD30
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